Validation Study of Oxford Classification of IgA Nephropathy: The Significance of Extracapillary Proliferation

Validating the oxford classification of IgA nephropathy.

The evolution of patients with IgA nephropathy (IgAN) varies greatly, and predictive tools are needed to assess confidently the risk for progression. Although in many studies clinical risk factors such as hypertension and proteinuria have consistently been linked to outcome, the independent value of pathology remains debated. Pathologists have developed a number of classifications over the year...

IgA Nephropathy and Significance of Immunostaining Data

Significance of extracapillary proliferation in IgA-nephropathy patients with regard to clinical and histopathological variables.

BACKGROUND AND AIM Extracapillary proliferation (crescent) was not included in the Oxford classification, although previous attempts to correlate the crescent with clinical outcomes have produced conflicting results. In this study, we investigated the clinical and morphological significance of extracapillary proliferation in a group of IgA nephropathy (IgAN) patients with regard to the Oxford c...

Validation of the Oxford Classification of IgA Nephropathy: A Single-Center Study in Korean Adults

BACKGROUND/AIMS The recently published Oxford classification of IgA nephropathy (IgAN) proposed a split system for histological grading, based on prognostic pathological features. This new classification system must be validated in a variety of cohorts. We investigated whether these pathological features were applicable to an adult Korean population. METHODS In total, 69 adult Korean patients...

Validation Study of the Oxford Classification for IgA Nephropathy in Korean Adults

Copyright © 2012 The Korean Association of Internal Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Received : August 13, 2012 Acce...